Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335293 | 0.81 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7420826 | 0.80 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27558503 | 0.80 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5348988 | 0.79 | PDE4B (0.56) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2371289 | 0.79 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7420229 | 0.78 | LDHA (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8769667 | 0.77 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5345029 | 0.77 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5345025 | 0.77 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28134189 | 0.77 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1350453-A | Method for treating exercise induced asthma | SMITHKLINE BEECHAM CORP (US) | 2002-05-22 | — | — | CN | disclosed |