SCHEMBL27558985

SCHEMBL27558985

COC(=O)c1cc(O)ccc1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.67
CA1 P00915 6/20 0.67
CA2 P00918 6/20 0.67
CA7 P43166 6/20 0.67
CA9 Q16790 6/20 0.67
CA14 Q9ULX7 6/20 0.67
PDK2 Q15119 1/20 0.67
PDK4 Q16654 1/20 0.67
ALDH1A1 P00352 3/20 0.53
TSHR P16473 2/20 0.53
ALOX5 P09917 1/20 0.53
PTGS2 P35354 1/20 0.53
MAPT P10636 3/20 0.49
GAA P10253 2/20 0.49
ESR2 Q92731 2/20 0.47
ESR1 P03372 1/20 0.47
HSD17B10 Q99714 2/20 0.47
EGFR P00533 2/20 0.47
MYC P01106 1/20 0.46
PTPN1 P18031 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6886739 0.92 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL158999 0.90 CA12 (0.74) CA12CA1CA2CA7CA9
SCHEMBL2952989 0.85 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL1956889 0.83 KDM4E (0.60) ALDH1A1MAPTPOLBLMNAMEN1
SCHEMBL338081 0.82 CFD (0.50) CA12CA1CA2CA7CA9
SCHEMBL22749357 0.82 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL10614787 0.81 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL177949 0.81 ALDH1A1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL31298798 0.81 ALDH1A1 (0.70) CA12CA1CA2CA7CA9
SCHEMBL10299395 0.81 CSNK2A1 (0.55) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109485573-A A kind of aromatic dicarboxylic acid ionic liquid and its preparation method and application 宝鸡文理学院 2019-03-19 CN claimed
CN-102161754-B Functional modification method for branched polyethylene glycol (PEG) derivative WUHAN UNION HOSPITAL 2012-06-13 CN claimed
CN-102161754-A Functional modification method for branched polyethylene glycol (PEG) derivative WUHAN UNION HOSPITAL 2011-08-24 CN claimed
CN-109485573-B Aromatic dicarboxylic acid ionic liquid and preparation method and application thereof 宝鸡文理学院 2021-04-30 CN disclosed
CN-109485573-A A kind of aromatic dicarboxylic acid ionic liquid and its preparation method and application 宝鸡文理学院 2019-03-19 CN disclosed
CN-102617578-B Imidazole derivative and medicine application thereof HUTCHISON WHAMPOA SHANGHAI LTD 2014-08-20 CN disclosed
CN-102617578-A Imidazole derivative and medicine application thereof HUTCHISON WHAMPOA SHANGHAI LTD 2012-08-01 CN disclosed
CN-102161754-B Functional modification method for branched polyethylene glycol (PEG) derivative WUHAN UNION HOSPITAL 2012-06-13 CN disclosed
CN-102161754-A Functional modification method for branched polyethylene glycol (PEG) derivative WUHAN UNION HOSPITAL 2011-08-24 CN disclosed
CN-101423518-A Imidazole derivative and medical application thereof HUTCHISON MEDIPHARMA SHANGHAI (CN) 2009-05-06 CN disclosed
CN-1282636-C Vitamin D analogues GALDERMA RES & DEV (FR) 2006-11-01 CN disclosed
CN-1332711-A Vitamin D analogues GALDERMA RES & DEV (FR) 2002-01-23 CN disclosed