Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18982890 | 0.88 | TRPA1 (0.47) | TRPA1GSRSLC6A4KDM4EALDH1A1 | |
| SCHEMBL14935978 | 0.84 | GSR (0.50) | TRPA1GSRKDM4EALDH1A1TAAR1 | |
| SCHEMBL16398170 | 0.84 | GSR (0.50) | TRPA1GSRKDM4EALDH1A1TAAR1 | |
| SCHEMBL14935912 | 0.84 | GSR (0.50) | TRPA1GSRKDM4EALDH1A1TAAR1 | |
| SCHEMBL20866401 | 0.82 | AOC3 (0.41) | SLC6A4TAAR1LMNARIPK1SLC6A2 | |
| SCHEMBL6297391 | 0.81 | SLC6A4 (0.39) | SLC6A4TAAR1LMNARIPK1SLC6A2 | |
| SCHEMBL1832901 | 0.80 | TRPA1 (0.48) | TRPA1GSRSLC6A4LMNARIPK1 | |
| SCHEMBL12530561 | 0.80 | TRPA1 (0.48) | TRPA1GSRSLC6A4LMNARIPK1 | |
| SCHEMBL8750393 | 0.79 | POLB (0.44) | SLC6A4KDM4EALDH1A1 | |
| SCHEMBL8750476 | 0.78 | LMNA (0.45) | TRPA1SLC6A4TAAR1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1380883-A | Novel derivatives and analogues of galanthamine | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2002-11-20 | — | — | CN | disclosed |