SCHEMBL27560

SCHEMBL27560

CCCCn1c(C)c(C2(c3c(C)n(CCCC)c4ccccc34)OC(=O)c3ccccc32)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.47
RORA P35398 2/20 0.47
RORC P51449 2/20 0.47
RORB Q92753 2/20 0.47
CNR2 P34972 8/20 0.46
CNR1 P21554 4/20 0.46
ALDH1A1 P00352 5/20 0.44
LMNA P02545 3/20 0.44
KDM4E B2RXH2 2/20 0.44
HPGD P15428 1/20 0.44
SLC6A3 Q01959 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GAA P10253 1/20 0.42
CFTR P13569 1/20 0.40
GOPC Q9HD26 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361500 1.00 PGR (0.47) PGRRORARORCRORBCNR2
SCHEMBL8608974 0.97 PGR (0.44) PGRRORARORCRORBCNR2
SCHEMBL7525264 0.97 CNR2 (0.47) PGRRORARORCRORBCNR2
SCHEMBL11003866 0.97 CNR2 (0.47) PGRRORARORCRORBCNR2
SCHEMBL2048334 0.97 CNR2 (0.47) PGRRORARORCRORBCNR2
SCHEMBL311993 0.95 CNR2 (0.47) PGRRORARORCRORBCNR2
SCHEMBL3234369 0.95 CNR2 (0.47) PGRRORARORCRORBCNR2
SCHEMBL29576122 0.95 CNR2 (0.47) PGRRORARORCRORBCNR2
SCHEMBL3219184 0.93 LMNA (0.44) PGRCNR2CNR1ALDH1A1LMNA
SCHEMBL18516808 0.92 CNR2 (0.44) PGRRORARORCRORBCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12202994-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2025-01-21 US claimed
US-12139626-B2 Irreversibly erasable ink composition having a discoloration agent SOCIéTé BIC (FR) 2024-11-12 US claimed
US-12043596-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2024-07-23 US claimed
CN-115298270-B Method for preparing thermochromic water-based gel ink composition and thermochromic water-based gel ink composition thereof 法国比克公司 2024-03-26 CN claimed
US-11920047-B2 Method for preparing thermochromic water-based gel ink compositions, and thermochromic water-based gel ink compositions thereof SOCIéTé BIC (FR) 2024-03-05 US claimed
EP-3859211-B1 HANDHELD LIGHTER WITH HIGH TEMPERATURE WARNING INDICATOR SOCIéTé BIC (FR) 2024-01-24 EP claimed
US-11814528-B2 Diester of bisphenol fluorene compounds and thermochromic pigment compositions comprising the same SOCIéTé BIC (FR) 2023-11-14 US claimed
US-11787226-B2 Eraser tool containing polyetheramine SOCIETE BIC (FR) 2023-10-17 US claimed
US-20230167325-A1 METHOD FOR PREPARING THERMOCHROMIC WATER-BASED GEL INK COMPOSITIONS, AND THERMOCHROMIC WATER-BASED GEL INK COMPOSITIONS THEREOF SOCIéTé BIC (FR) 2023-06-01 US claimed
US-11655387-B2 Thermochromic pigment compositions SOCIéTé BIC (FR) 2023-05-23 US claimed
US-6630242-B1 Containing colorless isobenzofuranone dye precursor; imparts preselected color to coating DSM N.V. (NL) 2003-10-07 US claimed
US-20030087178-A1 Photopolymerizable element for use as a flexographic printing plate and a process for preparing the plate from the element E. I. DU PONT DE NEMOURS AND COMPANY 2003-05-08 US claimed
EP-1251400-A2 A photopolymerizable element for use as a flexographic printing plate and a process for preparing the plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-10-23 EP claimed
US-20020110498-A1 Compositions able to indicate when they become inefficient in use FIRMENICH SA (CH) 2002-08-15 US claimed
US-20020057881-A1 Radiation-curable composition with simultaneous color formation during cure ALCATEL 2002-05-16 US claimed
US-6284706-B1 COLOR DEVELOPMENT LAYER ON SUBSTRATE NIPPON PAPER INDUSTRIES CO LTD (JP) 2001-09-04 US claimed
US-5942554-A EXPOSING A CURABLE MIXTURE OF POLYMERIC OR MONOMERIC COMPOUND, A COLOR PRECURSOR AND AN ONIUM SALT TO ACTINIC RADIATION TO EXCITE COLOR PRECURSOR AND CONVERTED TO A COLORED FORM BY OXIDATION OF COLOR PRECURSOR BY ONIUM SALT SPECTRA GROUP LIMITED, INC. (US) 1999-08-24 US claimed
US-5677107-A PHOTOHARDENABLE FILM WITH PHOTORESPONSIVE AGENT; IRRADIATING SELECTIVE PORTIONS OF CROSS-SECTIONAL PATTERNS THAT ARE TO BE COLORED DIFFERENTLY SPECTRA GROUP LIMITED, INC. (US) 1997-10-14 US claimed
US-5460647-A Mixture of wax, a leuco dye, a solvent together with a wax and color change-inducing compound which is Lewis acid induces color when contacted the leuco dyes; used in the form of crayons and pencils BINNEY & SMITH INC. (US) 1995-10-24 US claimed
US-4363664-A AQEOUS DISPERSION CONTAINING DYESTUFF PRECURSORS AND SURFACTANT STERLING DRUG INC. (US) 1982-12-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043596-B2 Thermochromic pigment compositions TYR, MITF, CRY2 PGR 2225/4885RORA 489/4885RORC 677/4885
US-12202994-B2 Thermochromic pigment compositions TYR, MITF, MC1R PGR 1676/4885RORA 626/4885RORC 756/4885
US-11814528-B2 Diester of bisphenol fluorene compounds and thermochromic pigment compositions comprising the same TYR, MITF, RB1 PGR 760/4885RORA 783/4885RORC 328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.