Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 5/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TAF1 | P21675 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739980 | 0.78 | ROCK2 (0.47) | NR3C1PGRNR3C2ARGRM5 | |
| SCHEMBL4798726 | 0.75 | CYP1A2 (0.40) | NR3C1PGRARGRM5BRD4 | |
| SCHEMBL5176001 | 0.72 | XDH (0.40) | GRM5BRD4TAF1BRPF1CREBBP | |
| SCHEMBL22253018 | 0.72 | SELL (0.41) | GRM5BRD4TAF1BRPF1CREBBP | |
| SCHEMBL860074 | 0.72 | AHR (0.50) | ARGRM5BRD4TAF1BRPF1 | |
| SCHEMBL15934119 | 0.72 | TDP1 (0.38) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL13085560 | 0.72 | NR3C1 (0.61) | NR3C1PGRNR3C2ARGRM5 | |
| SCHEMBL1394068 | 0.72 | TNF (0.42) | GRM5BRD4TAF1BRPF1CREBBP | |
| SCHEMBL24728224 | 0.71 | NR3C1 (0.34) | NR3C1PGRNR3C2ARTSHR | |
| SCHEMBL8578238 | 0.71 | ACHE (0.45) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1312154-C | Purine derivatives as kinase inhibitors | LILLY CO ELI (US) | 2007-04-25 | — | — | CN | disclosed |
| CN-1639165-A | Purine derivatives as kinase inhibitors | LILLY CO ELI (US) | 2005-07-13 | — | — | CN | disclosed |