Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811057 | 0.82 | KDM4E (0.48) | KDM4EPOLBGLAP2RY12RAB9A | |
| SCHEMBL18528819 | 0.78 | ALOX15 (0.70) | KDM4EP2RY12RAB9ATP53LMNA | |
| SCHEMBL31389285 | 0.78 | ALOX15 (0.70) | KDM4EP2RY12RAB9ATP53LMNA | |
| SCHEMBL31389238 | 0.78 | ALOX15 (0.57) | KDM4EP2RY12TP53LMNASMN1; SMN2 | |
| SCHEMBL423902 | 0.77 | CYP1A2 (0.55) | P2RY12TP53SMN1; SMN2NCF1 | |
| SCHEMBL7815368 | 0.77 | KDM4E (0.54) | KDM4EPOLBP2RY12RAB9ASLC2A1 | |
| SCHEMBL17433772 | 0.76 | PDE10A (0.54) | KDM4EPOLBGLARAB9ASMN1; SMN2 | |
| SCHEMBL7805302 | 0.75 | NCF1 (0.48) | KDM4ERAB9ASLC2A1SMN1; SMN2MEN1 | |
| SCHEMBL13036676 | 0.74 | ALOX15 (0.60) | KDM4ESLC2A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL4273454 | 0.74 | NCF1 (0.52) | KDM4EPOLBRAB9ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1307565-A | Quinolones used as MRS inhibitor and bactericides | SMITHKLINE BEECHAM PLC (GB) | 2001-08-08 | — | — | CN | disclosed |