Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTCH1 | P46531 | 1/20 | 0.32 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27567902 | 0.85 | CCKBR (0.39) | — | |
| SCHEMBL27567893 | 0.84 | CCKBR (0.32) | NOTCH1RBPJHCRTR1HCRTR2 | |
| SCHEMBL27567874 | 0.83 | NOTCH1 (0.39) | NOTCH1RBPJ | |
| SCHEMBL27567906 | 0.83 | KCNH2 (0.41) | NOTCH1RBPJ | |
| SCHEMBL28750573 | 0.81 | NOTCH1 (0.30) | NOTCH1RBPJCTSK | |
| SCHEMBL27587086 | 0.81 | NOTCH1 (0.36) | NOTCH1RBPJCTSKTDP1 | |
| SCHEMBL28747945 | 0.80 | OXTR (0.34) | — | |
| SCHEMBL27570557 | 0.80 | OXTR (0.35) | — | |
| SCHEMBL27587200 | 0.80 | REN (0.32) | — | |
| SCHEMBL4182463 | 0.79 | NOTCH1 (0.51) | NOTCH1RBPJ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1399634-A | Hydroxyalkanoyl aminolactams and related structure as inhibitors of A beta protein production | BRISTOL MYERS SQUIBB PHARMA IN (US) | 2003-02-26 | — | — | CN | disclosed |