Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 8/20 | 0.39 |
| ▸ | CCKAR | P32238 | 5/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27567874 | 0.90 | NOTCH1 (0.39) | CCKBROPRD1OPRK1 | |
| SCHEMBL27567906 | 0.86 | KCNH2 (0.41) | — | |
| SCHEMBL27567983 | 0.85 | CCKBR (0.36) | CCKBRCCKAR | |
| SCHEMBL27567893 | 0.85 | CCKBR (0.32) | CCKBR | |
| SCHEMBL27567945 | 0.85 | NOTCH1 (0.32) | — | |
| SCHEMBL28747945 | 0.84 | OXTR (0.34) | CCKBRCCKAR | |
| SCHEMBL27570557 | 0.83 | OXTR (0.35) | CCKBRCCKAR | |
| SCHEMBL27587200 | 0.83 | REN (0.32) | — | |
| SCHEMBL27587122 | 0.82 | REN (0.34) | CCKBR | |
| SCHEMBL27567973 | 0.80 | NOTCH1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1399634-A | Hydroxyalkanoyl aminolactams and related structure as inhibitors of A beta protein production | BRISTOL MYERS SQUIBB PHARMA IN (US) | 2003-02-26 | — | — | CN | claimed |
| CN-1399634-A | Hydroxyalkanoyl aminolactams and related structure as inhibitors of A beta protein production | BRISTOL MYERS SQUIBB PHARMA IN (US) | 2003-02-26 | — | — | CN | disclosed |