Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151416 | 0.72 | CYP1A2 (0.58) | CYP1A2KMT2ALMNAMEN1GPR119 | |
| SCHEMBL1456606 | 0.71 | CYP1A2 (0.67) | CYP1A2KMT2ALMNAMEN1GPR119 | |
| SCHEMBL8481298 | 0.70 | GPR119 (0.58) | CYP1A2KMT2ALMNAMEN1GPR119 | |
| SCHEMBL10650257 | 0.70 | PDE3B (0.62) | CYP1A2LMNAPDE4APDE4BPDE4C | |
| SCHEMBL13464837 | 0.68 | KMT2A (0.55) | CYP1A2KMT2ALMNAMEN1PDE4A | |
| SCHEMBL10648091 | 0.68 | PDE3B (0.43) | CYP1A2PDE3BPDE3APOLB | |
| SCHEMBL13970421 | 0.66 | CYP1A2 (0.50) | CYP1A2KMT2ALMNAMEN1GPR119 | |
| SCHEMBL29151105 | 0.66 | LMNA (0.56) | CYP1A2KMT2ALMNAMEN1GPR119 | |
| SCHEMBL30745172 | 0.66 | LMNA (0.56) | CYP1A2KMT2ALMNAMEN1GPR119 | |
| SCHEMBL10353459 | 0.63 | CYP1A2 (0.74) | CYP1A2KMT2ALMNAMEN1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1505514-A | Combination of aldose reductase inhibitors with cyclooxygenase-2 inhibitors | �Ʒ� | 2004-06-16 | — | — | CN | disclosed |
| CN-1390547-A | Therapy for tissue damage by local ischemia | PFIZER (US) | 2003-01-15 | — | — | CN | disclosed |