SCHEMBL27569986

SCHEMBL27569986

CC(C)CCCCCCCCCCCC(=O)n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TK1 P04183 2/20 0.46
PNP P00491 8/20 0.45
HPRT1 P00492 5/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
BLM P54132 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
CYP3A4 P08684 1/20 0.44
NFKB1 P19838 1/20 0.44
VCP P55072 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.44
HBB P68871 2/20 0.44
MAPK1 P28482 1/20 0.44
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
EDNRA P25101 1/20 0.43
HTR2A P28223 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7094400 0.82 TK1 (0.50) TK1PNPHPRT1MEN1KMT2A
SCHEMBL16351286 0.78 TK1 (0.71) TK1PNPHPRT1
SCHEMBL704009 0.77 XDH (0.50) TK1PNPHPRT1MEN1KMT2A
SCHEMBL3072984 0.76 PNP (0.51) TK1PNPHPRT1MEN1KMT2A
SCHEMBL27541246 0.75 XDH (0.58) TK1PNPHPRT1MEN1KMT2A
SCHEMBL27923065 0.75 XDH (0.55) TK1PNPHPRT1MEN1KMT2A
SCHEMBL16401839 0.73 MEN1 (0.51) PNPHPRT1MEN1KMT2ABLM
SCHEMBL28274963 0.73 HPRT1 (0.47) TK1PNPHPRT1MEN1KMT2A
SCHEMBL24529735 0.71 PNP (0.50) TK1PNPHPRT1MEN1KMT2A
SCHEMBL21516006 0.71 PNP (0.50) TK1PNPHPRT1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1343650-A Anticancer compound with particular structure YANG ZHENHUA (CN) 2002-04-10 CN claimed
CN-1343650-A Anticancer compound with particular structure YANG ZHENHUA (CN) 2002-04-10 CN disclosed