Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | HBB | P68871 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765224 | 0.84 | TK1 (0.57) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL7094400 | 0.83 | TK1 (0.50) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL5694098 | 0.83 | XDH (0.54) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL16401839 | 0.81 | MEN1 (0.51) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL218668 | 0.81 | XDH (0.53) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL27541246 | 0.81 | XDH (0.58) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL27923065 | 0.81 | XDH (0.55) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL4446276 | 0.79 | XDH (0.54) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL5347874 | 0.79 | PNP (0.50) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL4655346 | 0.78 | PNP (0.62) | PNPBLMHBBUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790843-B2 | Cypin polypeptide and fragments thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2010-09-07 | — | — | US | disclosed |
| US-20080182970-A1 | Using cypin in assays, diagnostics and treatment of cognitive disorders | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2008-07-31 | — | — | US | disclosed |
| US-7338769-B2 | Methods for identifying agonists of cypin | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-03-04 | — | — | US | disclosed |
| US-20050214822-A1 | Using cypin in assays, diagnostics and treatment of cognitive disorders | RUTGERS, THE STATE UNIVERSITY OF NEV | 2005-09-29 | — | — | US | disclosed |