Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PNP | P00491 | 6/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347874 | 0.90 | PNP (0.50) | TK1MEN1KMT2APNPBLM | |
| SCHEMBL7765224 | 0.85 | TK1 (0.57) | TK1MEN1KMT2APNPBLM | |
| SCHEMBL3072984 | 0.83 | PNP (0.51) | TK1MEN1KMT2APNPBLM | |
| SCHEMBL27569986 | 0.82 | TK1 (0.46) | TK1MEN1KMT2APNPBLM | |
| SCHEMBL218668 | 0.82 | XDH (0.53) | TK1MEN1KMT2APNPBLM | |
| SCHEMBL27541246 | 0.82 | XDH (0.58) | TK1MEN1KMT2APNPBLM | |
| SCHEMBL27923065 | 0.82 | XDH (0.55) | TK1MEN1KMT2APNPBLM | |
| SCHEMBL4446276 | 0.80 | XDH (0.54) | TK1MEN1KMT2APNPBLM | |
| SCHEMBL4655346 | 0.79 | PNP (0.62) | TK1PNPBLMUSP2TSHR | |
| SCHEMBL704009 | 0.78 | XDH (0.50) | TK1MEN1KMT2APNPBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023054391-A1 | NUCLEIC ACID STRAND CLEAVING METHOD, NUCLEIC ACID STRAND CLEAVING DEVICE, DOUBLE-STRANDED DNA PRODUCTION METHOD, AND DOUBLE-STRANDED DNA PRODUCTION DEVICE | 国立研究開発法人科学技術振興機構 | 2023-04-06 | — | — | WO | disclosed |
| EP-1334109-A2 | IMPROVED SYNTHESIS OF PURINE LOCKED NUCLEIC ACID ANALOGUES | Santaris Pharma A/S (DK) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002028875-A2 | IMPROVED SYNTHESIS OF PURINE LOCKED NUCLEIC ACID ANALOGUES | CUREON A/S (DK) | 2002-04-11 | — | — | WO | disclosed |
| WO-1997032589-A1 | COMBINATIONS FOR TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 1997-09-12 | — | — | WO | disclosed |
| WO-1997032604-A1 | ANTIPROLIFERATIVE COMBINATIONS, CONTAINING RAF-TARGETED OLIGONUCLEOTIDES AND CHEMOTHERAPEUTIC COMPOUNDS | NOVARTIS AG (CH) | 1997-09-12 | — | — | WO | disclosed |