Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640221 | 0.87 | CHRM1 (0.36) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| Ammonia Solution, Strong SCHEMBL10585168 | 0.85 | TDP1 (0.35) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL9577911 | 0.81 | CA2 (0.32) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL23383862 | 0.77 | CA2 (0.30) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL23383641 | 0.77 | RIPK1 (0.31) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL3378299 | 0.76 | ALDH1A1 (0.37) | TDP1ALDH1A1MAPT | |
| SCHEMBL20310958 | 0.76 | — | — | |
| SCHEMBL5003419 | 0.74 | CHRM1 (0.36) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL21470121 | 0.74 | CA2 (0.32) | CA2MAPK1 | |
| SCHEMBL52090 | 0.74 | ALDH1A1 (0.35) | ALDH1A1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1329614-A | Fused pyridazine derivatives, process for preparation of same and uses thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-02 | — | — | CN | disclosed |