Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10585168 | 0.97 | TDP1 (0.35) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL27574337 | 0.87 | CA2 (0.32) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL5003419 | 0.85 | CHRM1 (0.36) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL23383862 | 0.84 | CA2 (0.30) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL23383641 | 0.84 | RIPK1 (0.31) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL3378299 | 0.82 | ALDH1A1 (0.37) | TDP1ALDH1A1MAPT | |
| SCHEMBL21470121 | 0.80 | CA2 (0.32) | CA2MAPK1 | |
| SCHEMBL20954010 | 0.79 | HDAC1 (0.39) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL20143792 | 0.78 | CHRM1 (0.36) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL8668420 | 0.78 | CHRM1 (0.36) | CHRM1ADRA1AAKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2966099-B1 | PARTICLE SIZE DISTRIBUTION CONTROL THROUGH INTERNAL DONOR IN ZIEGLER-NATTA CATALYST | INDIAN OIL CORP LTD (IN) | 2020-03-11 | — | — | EP | claimed |
| EP-3018150-B1 | PROCESS FOR THE PREPARATION OF SPHERICAL CATALYST PARTICLES | INDIAN OIL CORP LTD (IN) | 2020-03-11 | — | — | EP | claimed |
| EP-3053935-B1 | CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2019-05-08 | — | — | EP | claimed |
| EP-3162819-B1 | IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | INDIAN OIL CORP LTD (IN) | 2018-09-05 | — | — | EP | claimed |
| EP-2897985-B1 | CATALYST FOR POLYMERIZATION OF OLEFINS AND PROCESS THEREOF | INDIAN OIL CORP LTD (IN) | 2017-03-08 | — | — | EP | claimed |
| US-10357590-B2 | Bioresorbable ceramic composition for forming a three dimensional scaffold | DePuy Synthes Products, Inc. (US) | 2019-07-23 | — | — | US | disclosed |
| US-10080750-B2 | Aminopyrimidine derivatives for use as modulators of kinase activity | MERCK PATENT GMBH (DE) | 2018-09-25 | — | — | US | disclosed |
| EP-2755958-B9 | AMINOPYRIMIDINE DERIVATIVES FOR USE AS MODULATORS OF KINASE ACTIVITY | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-20170360985-A9 | BIORESORBABLE CERAMIC COMPOSITION FOR FORMING A THREE DIMENSIONAL SCAFFOLD | DEPUY SYNTHES PRODUCTS INC (US) | 2017-12-21 | — | — | US | disclosed |
| US-20170340770-A1 | HYDRAULIC CEMENT-BASED IMPLANT MATERIAL AND USE THEREOF | INNOTERE GMBH (DE) | 2017-11-30 | — | — | US | disclosed |
| US-9764057-B2 | Hydraulic cement-based implant material and use thereof | INNOTERE GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| EP-2755958-B1 | AMINOPYRIMIDINE DERIVATIVES FOR USE AS MODULATORS OF KINASE ACTIVITY | MERCK PATENT GMBH (DE) | 2017-08-09 | — | — | EP | disclosed |
| WO-2002014482-A2 | POLYKETIDES AND THEIR SYNTHESIS | BIOTICA TECHNOLOGY LIMITED (GB) | 2002-02-21 | — | — | WO | disclosed |
| EP-1012376-A2 | OXIDATION AND BLEACHING SYSTEM WITH ENZYMATICALLY PRODUCED OXIDIZING AGENTS | Blume, Hildegard (DE) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998059108-A2 | OXIDATION AND BLEACHING SYSTEM WITH ENZYMATICALLY PRODUCED OXIDIZING AGENTS | BLUME, HILDEGARD (DE) | 1998-12-30 | — | — | WO | disclosed |
| US-4309544-A | CONDENSATION OF 2-METHYLENE-QUINUCLIDIN-3-ONE WITH A KETONE OR AN | THE PURDUE FREDERICK COMPANY (US) | 1982-01-05 | — | — | US | disclosed |
| US-4262103-A | SOLUTION POLYMERIZATION IN PRESENCE OF CATALYST MIXTURE OF ORGANOALUMINUM COMPOUND AND MOLYBDENUM SALT | THE B. F. GOODRICH COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4226996-A | 4-SUBSTITUTED-6-OXA-1-AZATRICYCLO/4.2.2.0.2.7/DODECAN-5-ONE SALT | THE PURDUE FREDERICK COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-4183938-A | 1,8-Ethano-5-oxo-octa- and -decahydroquinolines and mydriatic compositions thereof | THE PURDUE FREDERICK COMPANY (US) | 1980-01-15 | — | — | US | disclosed |
| US-4083985-A | 6-Oxa-1-aza tricyclo dodecan-5-ones as psychomotor stimulators | THE PURDUE FREDERICK COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10080750-B2 | Aminopyrimidine derivatives for use as modulators of kinase activity | CDK6, TK1, MAP3K19 | CHRM1 4245/4885ADRA1A 2375/4885AKR1A1 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.