Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495840 | 0.80 | BCAT2 (0.62) | BCAT2MAPK8MAPK10SLC9A1PKM | |
| SCHEMBL4717953 | 0.78 | BCAT2 (0.64) | BCAT2MAPK8MAPK10SLC9A1ALDH1A1 | |
| SCHEMBL2279587 | 0.77 | BCAT2 (0.47) | BCAT2MAPK8MAPK10PKMALDH1A1 | |
| SCHEMBL7472100 | 0.77 | BCAT2 (0.62) | BCAT2MAPK8MAPK10SLC9A1PKM | |
| SCHEMBL28012573 | 0.76 | BCAT2 (0.57) | BCAT2MAPK8SLC9A1ALDH1A1KDM4E | |
| SCHEMBL27574584 | 0.76 | MAPK8 (0.47) | BCAT2MAPK8MAPK10FGFR1FGFR2 | |
| SCHEMBL6961376 | 0.74 | BCAT2 (0.58) | BCAT2MAPK8MAPK10PKMALDH1A1 | |
| SCHEMBL6034332 | 0.74 | BCAT2 (0.46) | BCAT2MAPK8MAPK10KMT2ARORC | |
| SCHEMBL4445671 | 0.74 | BCAT2 (1.00) | BCAT2MAPK8MAPK10ALDH1A1KMT2A | |
| SCHEMBL528444 | 0.74 | BCAT2 (0.55) | BCAT2FGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1447794-A | Novel compounds | ASTRAZENECA AB (SE) | 2003-10-08 | — | — | CN | disclosed |