Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3077087 | 0.86 | PKM (0.43) | BCAT2PKMMAPK8MAPK10KMT2A | |
| SCHEMBL4045273 | 0.83 | PKM (0.41) | BCAT2PKMMAPK8MAPK10ALDH1A1 | |
| SCHEMBL31322640 | 0.83 | BCAT2 (0.52) | BCAT2PKMMAPK8MAPK10KMT2A | |
| SCHEMBL15286612 | 0.82 | GPR35 (0.43) | BCAT2PKMALDH1A1 | |
| SCHEMBL21554317 | 0.82 | ALOX5 (0.39) | BCAT2PKMMAPK8MAPK10KMT2A | |
| SCHEMBL3814101 | 0.81 | CDK8 (0.43) | BCAT2PKMMAPK8MAPK10KMT2A | |
| SCHEMBL14614093 | 0.81 | MAPK8 (0.42) | PKMMAPK8MAPK10KMT2AALDH1A1 | |
| SCHEMBL2065269 | 0.81 | ABCC1 (0.50) | KMT2AALDH1A1MEN1MAPK1GSK3B | |
| SCHEMBL6928575 | 0.81 | GPR35 (0.46) | PKMKMT2AMEN1MAPK1 | |
| SCHEMBL21356996 | 0.80 | BCAT2 (0.44) | BCAT2PKMMAPK8MAPK10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025075821-A1 | METHODS AND COMPOSITIONS FOR IMPROVING HERBICIDE DAMAGE RECOVERY IN CROPS | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-10 | — | — | WO | claimed |
| EP-2523552-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS MARK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-11-21 | — | — | EP | claimed |
| WO-2011087999-A1 | PYRAZOLO[1,5-A]PYRIMIDINES AS MARK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-21 | — | — | WO | claimed |
| WO-2025075821-A1 | METHODS AND COMPOSITIONS FOR IMPROVING HERBICIDE DAMAGE RECOVERY IN CROPS | SYNGENTA CROP PROTECTION AG (CH) | 2025-04-10 | — | — | WO | disclosed |
| US-20230101819-A1 | SMYD Inhibitors | EPIZYME INC (US) | 2023-03-30 | — | — | US | disclosed |
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | disclosed |
| CN-110407827-A | The new crystalline form of GCC-4401C and pharmaceutical composition comprising the new crystalline form | GREEN CROSS CORP | 2019-11-05 | — | — | CN | disclosed |
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | disclosed |
| US-10266526-B2 | Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer | Epizyme, Inc. (US) | 2019-04-23 | — | — | US | disclosed |
| CN-106008491-B | A kind of preparation method of razaxaban | 苏州汇和药业有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-108152412-A | A kind of method with liquid chromatography for separating and determining razaxaban and its in relation to substance | 乐普药业股份有限公司 | 2018-06-12 | — | — | CN | disclosed |
| US-20170355695-A1 | SMYD Inhibitors | Epizyme, Inc. (US) | 2017-12-14 | — | — | US | disclosed |
| CN-104478866-B | Oxazolidinone compounds and its application in medicine | 广东东阳光药业有限公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-105593232-A | Benzoxazoloxazinone compounds as coagulation factor Xa inhibitors | NORTH CHINA PHARMACEUTICAL NEW DRUG R & D CO LTD | 2016-05-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266526-B2 | Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer | SMYD3, SMYD2, SNRPD3 | BCAT2 1595/4885PKM 3509/4885MAPK8 3598/4885 |
| US-20170355695-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | BCAT2 544/4885PKM 3668/4885MAPK8 3861/4885 |
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | BCAT2 565/4885PKM 3671/4885MAPK8 3851/4885 |
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | BCAT2 649/4885PKM 3834/4885MAPK8 3713/4885 |
| US-20230101819-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | BCAT2 538/4885PKM 3671/4885MAPK8 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.