Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753879 | 0.83 | PARP1 (0.68) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL29503529 | 0.83 | PARP1 (0.68) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL186545 | 0.83 | PARP1 (0.68) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL14406 | 0.81 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL29382709 | 0.81 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL76212 | 0.81 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL142937 | 0.81 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL29639739 | 0.81 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| SCHEMBL15264066 | 0.81 | PARP1 (0.65) | PARP1HDAC8HDAC6SMN1; SMN2HPGD | |
| Ammonia Solution, Strong SCHEMBL1667008 | 0.79 | PARP1 (0.63) | PARP1HDAC8HDAC6SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | claimed |
| EP-2892343-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-07-15 | — | — | EP | claimed |
| WO-2014037349-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2014-03-13 | — | — | WO | claimed |
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | THE KITASATO INSTITUTE (JP) | 2011-07-28 | — | — | US | claimed |
| EP-2228376-A1 | PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY | The Kitasato Institute (JP) | 2010-09-15 | — | — | EP | claimed |
| US-20030036661-A1 | 2-Aroyl-4-acyl paclitaxel (taxol) analogs | BRISTOL-MYERS SQUIBB COMPANY | 2003-02-20 | — | — | US | claimed |
| EP-1067923-A4 | 2-AROYL-4-ACYL PACLITAXEL (TAXOL) ANALOGS | BRISTOL MYERS SQUIBB CO (US) | 2002-11-13 | — | — | EP | claimed |
| EP-1067923-A1 | 2-AROYL-4-ACYL PACLITAXEL (TAXOL) ANALOGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999033462-A1 | 2-AROYL-4-ACYL PACLITAXEL (TAXOL) ANALOGS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1999-07-08 | — | — | WO | claimed |
| EP-0171064-B1 | Azetidinone derivative and processes for production thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-07-12 | — | — | EP | claimed |
| EP-0249999-A2 | Triazolyl ethyl ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1987-12-23 | — | — | EP | claimed |
| US-11873468-B2 | Polymers for the treatment of surfaces | HENKEL AG & CO. KGAA (DE) | 2024-01-16 | — | — | US | disclosed |
| US-11591426-B2 | Copolymer, wetting agent, medical device, and method for producing same | TORAY INDUSTRIES, INC. (JP) | 2023-02-28 | — | — | US | disclosed |
| EP-3438144-B1 | COPOLYMER, WETTING AGENT, MEDICAL DEVICE, AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2021029158-A1 | SULFONAMIDE COMPOUND, NONIONIC PHOTOACID GENERATOR, AND PHOTOLITHOGRAPHY RESIN COMPOSITION | サンアプロ株式会社 | 2021-02-18 | — | — | WO | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0249999-A2 | Triazolyl ethyl ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1987-12-23 | — | — | EP | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | CAT, HSF1, HPD | PARP1 3424/4885HDAC8 2868/4885HDAC6 1045/4885 |
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | ACAT2, ACAT1, AGPAT2 | PARP1 4377/4885HDAC8 460/4885HDAC6 580/4885 |
| US-20030036661-A1 | 2-Aroyl-4-acyl paclitaxel (taxol) analogs | HDAC6, HDAC3, ACAT2 | PARP1 25/4885HDAC8 29/4885HDAC6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.