Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.52 |
| ▸ | USP5 | P45974 | 9/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960132 | 0.78 | USP30 (0.57) | MMP2MMP13USP30USP5MMP3 | |
| SCHEMBL4960919 | 0.77 | CA12 (0.54) | MMP2MMP13USP30USP5MMP3 | |
| SCHEMBL4964431 | 0.76 | MMP2 (0.54) | MMP2MMP13USP30USP5MMP3 | |
| SCHEMBL31527727 | 0.76 | CA12 (0.56) | MMP2MMP13USP30USP5MMP3 | |
| SCHEMBL27640069 | 0.75 | CA12 (0.49) | MMP2MMP13CA12CA1CA2 | |
| SCHEMBL7569013 | 0.74 | NLRP3 (0.47) | — | |
| SCHEMBL26213661 | 0.74 | HSD11B1 (0.52) | MMP2MMP13USP30USP5MMP3 | |
| SCHEMBL5490962 | 0.73 | KCNH2 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9320214 | 0.73 | NPY5R (0.58) | MMP2MMP13USP30USP5HDAC6 | |
| SCHEMBL21033833 | 0.73 | HSD11B1 (0.51) | MMP2MMP13USP30USP5MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1370526-A | Treating method of nuclear factor-KB mediated diseases and dysfuction | WANER LONGBER CO (US) | 2002-09-25 | — | — | CN | claimed |
| CN-1370526-A | Treating method of nuclear factor-KB mediated diseases and dysfuction | WANER LONGBER CO (US) | 2002-09-25 | — | — | CN | disclosed |