Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23279486 | 0.84 | MEN1 (0.41) | MEN1KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL18256513 | 0.84 | MEN1 (0.41) | MEN1KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL2758305 | 0.83 | MEN1 (0.43) | MEN1KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL23072695 | 0.83 | ESR1 (0.59) | KMT2ATSHRNPC1RAB9AESR1 | |
| SCHEMBL7273379 | 0.83 | ESR1 (0.59) | KMT2ATSHRNPC1RAB9AESR1 | |
| SCHEMBL18328239 | 0.81 | PTPRB (0.55) | MEN1KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL7030656 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7030654 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL31299894 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8031433 | 0.80 | TP53 (0.51) | MEN1KMT2ALMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9302990-B2 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2016-04-05 | — | — | US | disclosed |
| US-8546578-B2 | Iodonium Cyclophanes for SECURE arene functionalization | NUTECH VENTURES (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | NATIONAL SCIENCE FOUNDATION | 2012-01-05 | — | — | US | disclosed |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2011-12-22 | — | — | US | disclosed |
| US-20110190505-A1 | Iodonium Cyclophanes for SECURE Arene Functionalization | NATIONAL SCIENCE FOUNDATION | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004417-A1 | FLUORINATION OF AROMATIC RING SYSTEMS | PFAS, SLC43A1, DDC | MEN1 744/4885KMT2A 1182/4885LMNA 2489/4885 |
| US-20110190505-A1 | Iodonium Cyclophanes for SECURE Arene Functionalization | ABL1, SLC7A5, DDC | MEN1 2256/4885KMT2A 1869/4885LMNA 3537/4885 |
| US-20110313170-A1 | Fluorination of Aromatic Ring Systems | PFAS, SLC43A1, DDC | MEN1 744/4885KMT2A 1182/4885LMNA 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.