Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | DDX3X | O00571 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27840816 | 0.73 | KDM4E (0.49) | KDM4EHPGDHSD17B10RAB9AGAA | |
| SCHEMBL31229740 | 0.73 | ALPL (0.46) | KDM4EHPGDHSD17B10RAB9AGAA | |
| SCHEMBL22639991 | 0.70 | DHODH (0.59) | KDM4EHPGDHSD17B10DHODH | |
| SCHEMBL373592 | 0.70 | DAO (0.64) | KDM4ERIPK1GAAALDH1A1TSHR | |
| SCHEMBL10321662 | 0.70 | KDM4E (0.52) | KDM4EHPGDHSD17B10RAB9AGAA | |
| SCHEMBL10322786 | 0.67 | KDM4E (0.45) | KDM4EALDH1A1CYP1A2MAPT | |
| SCHEMBL31339998 | 0.67 | ALDH1A1 (0.40) | KDM4EHPGDHSD17B10RAB9AGAA | |
| SCHEMBL19520848 | 0.66 | MEN1 (0.73) | KDM4EHPGDHSD17B10DHODHRAB9A | |
| SCHEMBL31394 | 0.66 | KDM4E (0.59) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL29364659 | 0.66 | KDM4E (0.59) | KDM4EHPGDHSD17B10GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1476442-A | Pyridine derivatives with IKB-kinase (IKK-beta) INhibiting activity | — | 2004-02-18 | — | — | CN | disclosed |