Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CDK4 | P11802 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CCND1 | P24385 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580610 | 0.92 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL7958648 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL28580926 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL7940135 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL28058027 | 0.77 | HTR5A (0.59) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| Iodide SCHEMBL25336773 | 0.76 | MEN1 (0.56) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| Hydrochloric Acid SCHEMBL9451439 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL4532583 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL31186642 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL14881174 | 0.75 | MAPT (0.58) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1523992-A | Compositions and methods for treating amyloidosis | ʺ��ѧ | 2004-08-25 | — | — | CN | claimed |