Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | AOC2 | O75106 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27298812 | 0.82 | LMNA (0.45) | MAOBKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL10991214 | 0.82 | ESR1 (0.43) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL27996154 | 0.82 | KMT2A (0.49) | KMT2AMAPTHTT | |
| SCHEMBL27754997 | 0.81 | CYP1A2 (0.44) | MAOBMAOAKMT2ASMN1; SMN2ESR1 | |
| SCHEMBL5642116 | 0.80 | KMT2A (0.63) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL905941 | 0.80 | ELANE (0.49) | MAOBAOC2DAOMAOAKMT2A | |
| SCHEMBL27584317 | 0.79 | PPARG (0.43) | MAOBKMT2ASMN1; SMN2ESR1MEN1 | |
| SCHEMBL3976536 | 0.79 | MAOB (0.41) | MAOBAOC2DAOMAOAKMT2A | |
| SCHEMBL8467275 | 0.78 | ELANE (0.47) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL27996167 | 0.78 | LTA4H (0.48) | SMN1; SMN2ELANENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220058-A | Serine racemase inhibitor | NAT UNIV CORP UNIV TOYAMA | 2014-12-17 | — | — | CN | disclosed |
| CN-100376571-C | 6-substituted pyrido-pyrimidines | HOFFMANN LA ROCHE (CH) | 2008-03-26 | — | — | CN | disclosed |
| CN-1503672-A | 6-substituted pyridopyrimidines | - | 2004-06-09 | — | — | CN | disclosed |