Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272772 | 0.79 | NPC1 (0.50) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL19864312 | 0.78 | MAPK14 (0.73) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL13633790 | 0.77 | TP53 (0.50) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL4883972 | 0.77 | TP53 (0.75) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL869242 | 0.77 | GAA (0.51) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL14195802 | 0.76 | NPC1 (0.56) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL22925728 | 0.76 | KDM4E (0.48) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL8192267 | 0.75 | ENPP3 (0.42) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL2706143 | 0.75 | NPC1 (0.52) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11514956 | 0.74 | IKBKB (0.37) | RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644099-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160355682-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-20150050685-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2015-02-19 | — | — | US | disclosed |
| US-8822695-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-17 | — | — | US | disclosed |
| US-8415477-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | RAB9A 1942/4885NPC1 2968/4885MEN1 1525/4885 |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | RAB9A 1942/4885NPC1 2968/4885MEN1 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.