SCHEMBL27586255

SCHEMBL27586255

CCOc1cccc(CN2CC(=O)NC2=O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HCRTR1 O43613 1/20 0.44
HCRTR2 O43614 1/20 0.44
FAAH O00519 1/20 0.44
HTR1A P08908 1/20 0.43
DRD2 P14416 1/20 0.43
HTR2B P41595 1/20 0.43
DDB1 Q16531 2/20 0.42
CRBN Q96SW2 2/20 0.42
EPHX2 P34913 1/20 0.42
CMA1 P23946 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
GAA P10253 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8984067 0.77 HCRTR1 (0.46) HSD17B10MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL5182904 0.76 EPHX2 (0.47) MAPTMEN1KMT2AFAAHDDB1
SCHEMBL30065107 0.76 EPHX2 (0.47) MAPTMEN1KMT2ADRD2DDB1
SCHEMBL9850086 0.74 DDB1 (0.69) MEN1KMT2ADDB1CRBNEPHX2
SCHEMBL1011633 0.74 DDB1 (0.69) MEN1KMT2ADDB1CRBNEPHX2
SCHEMBL31773 0.74 LOXL2 (0.52) MAPTSMN1; SMN2KDM4E
SCHEMBL9850110 0.73 DDB1 (0.67) MEN1KMT2ADDB1CRBNEPHX2
SCHEMBL3140629 0.72 ENPP2 (0.46) MAPTMEN1KMT2ADDB1CRBN
SCHEMBL31768 0.72 CYP2D6 (0.54) MAPTMEN1KMT2ADDB1CRBN
SCHEMBL6101068 0.71 GAA (0.73) MAPTMEN1KMT2ASMN1; SMN2CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1521558-A Silver halide color photographic material 柯尼卡美能达控股株式会社 2004-08-18 CN disclosed