Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | SDHB | P21912 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27586255 | 0.77 | HSD17B10 (0.52) | HCRTR1HCRTR2FAAHHTR1ADRD2 | |
| SCHEMBL4892237 | 0.75 | EPHX2 (0.45) | CMA1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7511407 | 0.70 | HTR1A (0.57) | FAAHHTR1ADRD2HTR2BCHRM3 | |
| SCHEMBL11848182 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1MAPTKMT2ATP53 | |
| SCHEMBL13293711 | 0.69 | ALDH1A1 (0.61) | FAAHHTR1ADRD2HTR2BSMN1; SMN2 | |
| SCHEMBL4353971 | 0.68 | CHRM2 (0.58) | CHRM2CHRM1CHRM3SMN1; SMN2MAPT | |
| SCHEMBL131598 | 0.68 | TP53 (0.59) | CHRM2CHRM1CHRM3SMN1; SMN2DHFR | |
| SCHEMBL5247746 | 0.68 | TP53 (0.59) | HSD17B10CHRM2CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL31061915 | 0.68 | TP53 (0.59) | CHRM2CHRM1CHRM3SMN1; SMN2DHFR | |
| SCHEMBL24187836 | 0.68 | TNIK (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498513-A | BENZOTRIAZOLE DIR COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |