Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15779182 | 0.86 | MTNR1A (0.46) | MTNR1AMTNR1BPARP1HSD17B2HSD17B1 | |
| SCHEMBL27605653 | 0.85 | CYP3A4 (0.44) | MTNR1AMTNR1BPARP1HSD17B2HSD17B1 | |
| SCHEMBL28382188 | 0.85 | PARP1 (0.56) | MTNR1AMTNR1BPARP1HSD17B2HSD17B1 | |
| SCHEMBL7614229 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BPARP1HSD17B2HSD17B1 | |
| SCHEMBL27500838 | 0.84 | TRPM8 (0.43) | MTNR1AMTNR1BPARP1LMNACYP1A2 | |
| SCHEMBL27556170 | 0.81 | TP53 (0.44) | MTNR1AMTNR1BPARP1HSD17B2HSD17B1 | |
| SCHEMBL27605656 | 0.81 | RYR2 (0.39) | MTNR1AMTNR1BPARP1HSD17B2HSD17B1 | |
| SCHEMBL27605751 | 0.81 | TP53 (0.46) | MTNR1AMTNR1BPARP1HSD17B2HSD17B1 | |
| SCHEMBL27605646 | 0.80 | MAPT (0.46) | LMNAHPGDMAOBTP53HTT | |
| SCHEMBL27587725 | 0.80 | ESR1 (0.50) | MTNR1AMTNR1BPARP1HSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |