Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605699 | 0.93 | GPR35 (0.46) | GPR35GAATHRBKMT2AMEN1 | |
| SCHEMBL27587702 | 0.88 | MGLL (0.45) | GPR35GAATHRBKMT2AMEN1 | |
| SCHEMBL27587723 | 0.87 | MEN1 (0.42) | GPR35GAATHRBKMT2AMEN1 | |
| SCHEMBL27587711 | 0.87 | GPR35 (0.51) | GPR35GAATHRBKMT2AALDH1A1 | |
| SCHEMBL6824083 | 0.85 | L3MBTL1 (0.42) | GPR35GAATHRBKMT2APOLB | |
| SCHEMBL9488095 | 0.85 | PTGS2 (0.41) | GPR35GAATHRBPOLBALDH1A1 | |
| SCHEMBL3018832 | 0.85 | MAPT (0.48) | GAAKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL9267193 | 0.85 | GPR35 (0.39) | GPR35GAATHRBKMT2AMEN1 | |
| SCHEMBL27605684 | 0.83 | MEN1 (0.47) | KMT2AMEN1ALDH1A1CXCR1CXCR2 | |
| SCHEMBL29967745 | 0.82 | CXCR2 (0.49) | GPR35GAATHRBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |