Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784339 | 1.00 | UMPS (0.44) | UMPSLMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6790961 | 1.00 | UMPS (0.44) | UMPSLMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL27606205 | 1.00 | UMPS (0.44) | UMPSLMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL5878336 | 0.90 | UMPS (0.44) | UMPSLMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6796400 | 0.84 | KDM4E (0.45) | ALDH1A1GLAKDM4EGAASLC5A2 | |
| SCHEMBL6932964 | 0.84 | KDM4E (0.45) | ALDH1A1GLAKDM4EGAASLC5A2 | |
| SCHEMBL8973945 | 0.81 | PYGL (0.43) | PYGLSLC5A2 | |
| SCHEMBL15968709 | 0.81 | SLC5A2 (0.46) | UMPSPYGLSLC5A2 | |
| Ribose (Furanose) SCHEMBL17479515 | 0.78 | TDP1 (0.47) | UMPSLMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6789543 | 0.78 | PYGL (0.41) | PYGLMAPTSLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1527836-A | Antiviral agents for treatment of flaviviridae infections | — | 2004-09-08 | — | — | CN | disclosed |