Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.34 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27606414 | 0.80 | HRH3 (0.55) | ALDH1A1TSHRTAAR1NOS1PARP1 | |
| SCHEMBL27588484 | 0.79 | CDK8 (0.42) | TAAR1NOS1HRH3 | |
| SCHEMBL27606407 | 0.75 | ALDH1A1 (0.40) | HTR7ATP4AATP4BALDH1A1TSHR | |
| SCHEMBL3464184 | 0.72 | TAAR1 (0.67) | HTR7ALDH1A1TSHRTAAR1NOS1 | |
| SCHEMBL29864624 | 0.72 | TAAR1 (0.67) | HTR7ALDH1A1TSHRTAAR1NOS1 | |
| SCHEMBL989636 | 0.71 | ALDH1A1 (0.67) | HTR7ALDH1A1TSHRTAAR1NOS1 | |
| SCHEMBL20031290 | 0.70 | PRKCI (0.61) | HTR7ATP4AATP4BALDH1A1TSHR | |
| SCHEMBL27606266 | 0.69 | MAOA (0.47) | ALDH1A1TSHRHPGD | |
| SCHEMBL27588599 | 0.69 | DYRK1A (0.50) | — | |
| SCHEMBL3140283 | 0.67 | TAAR1 (0.51) | HTR7ATP4AATP4BALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |