Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27606576 | 0.82 | HRH3 (0.50) | LOXL2TAAR1CYP2A6HRH3ADRB2 | |
| SCHEMBL27588588 | 0.79 | HTR7 (0.46) | TAAR1NOS1HRH3 | |
| SCHEMBL27606266 | 0.77 | MAOA (0.47) | ENPP2 | |
| SCHEMBL3791745 | 0.74 | LOXL2 (0.60) | CDK8PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL16719914 | 0.72 | PNMT (0.40) | CDK8PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL27588592 | 0.72 | PNMT (0.40) | PNMTENPP2LOXL2NOS3NOS1 | |
| SCHEMBL27588599 | 0.69 | DYRK1A (0.50) | CYP2A6 | |
| SCHEMBL3794460 | 0.69 | TAAR1 (0.70) | CDK8PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL43554 | 0.69 | TAAR1 (0.70) | PNMTENPP2LOXL2TAAR1CFD | |
| SCHEMBL29400616 | 0.69 | TAAR1 (0.70) | PNMTENPP2LOXL2TAAR1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |