Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MECP2 | P51608 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588484 | 0.77 | CDK8 (0.42) | ENPP2 | |
| SCHEMBL27588743 | 0.75 | ALDH1A1 (0.43) | MEN1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL27588599 | 0.73 | DYRK1A (0.50) | CYP3A4KDM4EMAPTKMT2A | |
| SCHEMBL29403794 | 0.71 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL251095 | 0.71 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL30500254 | 0.71 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL31131352 | 0.69 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL | |
| Water SCHEMBL2444002 | 0.69 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL | |
| Methane SCHEMBL21853746 | 0.69 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL | |
| Ammonia Solution, Strong SCHEMBL21296174 | 0.69 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |