Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HPD | P32754 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981648 | 0.87 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10KDM4EBRD4 | |
| SCHEMBL4859467 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HSD17B10KDM4EBRD4 | |
| SCHEMBL4860594 | 0.83 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1HSD17B10KDM4EBRD4 | |
| SCHEMBL4200128 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HSD17B10KDM4EBRD4 | |
| SCHEMBL4190022 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1HSD17B10KDM4EBRD4 | |
| SCHEMBL9484562 | 0.77 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL27611288 | 0.77 | HSD17B3 (0.45) | ALDH1A1HSD17B10KDM4ESIGMAR1HSD17B3 | |
| SCHEMBL6034799 | 0.76 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HSD17B10KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL4860132 | 0.75 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HSD17B10KDM4EBRD4 | |
| SCHEMBL1422842 | 0.75 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1HSD17B10KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589153-A | Prevention or treatment of urinary disorders | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-03-02 | — | — | CN | disclosed |