Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 2/20 | 0.56 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593085 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL4859467 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL4860594 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL4190022 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL6034799 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| Hydrochloric Acid SCHEMBL4860132 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL1119999 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL1422842 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL6035084 | 0.73 | THRA (0.49) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL23846427 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HSD17B10BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138533-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-21 | — | — | US | disclosed |
| US-20050197362-A1 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197362-A1 | Preventives/remedies for urinary disturbance | ACHE, BPHL, CHRM1 | SMN1; SMN2 1472/4885ALDH1A1 118/4885HSD17B10 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.