Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211640 | 0.81 | RAB9A (0.53) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL2732976 | 0.73 | HDAC1 (0.66) | KDR | |
| SCHEMBL5583228 | 0.72 | DHFR (0.54) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL6484790 | 0.72 | MAPT (0.57) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL1064412 | 0.70 | L3MBTL1 (0.53) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL3560484 | 0.70 | LMNA (0.56) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL21697974 | 0.68 | L3MBTL1 (0.53) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL28610112 | 0.68 | MAPT (1.00) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL28039966 | 0.67 | MAPT (0.74) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL8065663 | 0.67 | MAPT (0.74) | RAB9AGAAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088805-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-01-03 | — | — | US | disclosed |