Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | CPS1 | P31327 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580862 | 0.81 | KDM4E (0.46) | CYP11B1CYP11B2TBXAS1MAPT | |
| SCHEMBL4277304 | 0.72 | GSK3A (0.42) | KMT2ATBXAS1CDK2TP53 | |
| SCHEMBL8335586 | 0.71 | NOS2 (0.42) | KMT2ACYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL7290470 | 0.70 | NPC1 (0.49) | KMT2AMAPT | |
| SCHEMBL7706502 | 0.67 | GAA (0.55) | SMN1; SMN2 | |
| SCHEMBL4815855 | 0.65 | KDM4E (0.53) | CYP19A1CYP11B1CYP11B2TBXAS1MAPT | |
| SCHEMBL27588449 | 0.65 | KDM4E (0.60) | — | |
| SCHEMBL5774733 | 0.65 | CYP24A1 (0.36) | KMT2ACYP24A1CYP19A1TBXAS1MAPT | |
| SCHEMBL6775905 | 0.65 | AHR (0.38) | MAPT | |
| SCHEMBL11110140 | 0.64 | CYP19A1 (0.55) | KMT2ACYP19A1TBXAS1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1452619-A | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity | SMITHKLINE BEECHAM PLC (GB) | 2003-10-29 | — | — | CN | disclosed |