Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533005 | 0.84 | HTT (0.47) | PKMTSHRHTR6HTTCHRM2 | |
| SCHEMBL6302182 | 0.79 | CHRM2 (0.67) | PKMTSHRHTR6CHRM2CHRM5 | |
| SCHEMBL366283 | 0.77 | CYP2C19 (0.62) | TSHRMEN1CYP2C19KMT2AKCNA4 | |
| SCHEMBL14628573 | 0.77 | ENPP2 (0.43) | HTT | |
| SCHEMBL2533012 | 0.76 | GAA (0.47) | TSHRHTR6HTTMEN1KMT2A | |
| (Phenylsulfonyl)Benzene SCHEMBL3421893 | 0.75 | HTR6 (0.74) | PKMTSHRHTR6MEN1KMT2A | |
| SCHEMBL9451016 | 0.74 | MEN1 (0.44) | TSHRHTTMEN1CYP2C19KMT2A | |
| SCHEMBL5051390 | 0.74 | HTR6 (0.93) | PKMTSHRHTR6HTTKMT2A | |
| (Phenylsulfonyl)Benzene SCHEMBL5018081 | 0.74 | HTR6 (0.93) | PKMTSHRHTR6LOXPOLB | |
| SCHEMBL3597677 | 0.74 | MEN1 (0.48) | TSHRCHRM2MEN1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610547-A | N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor | LILLY CO ELI (US) | 2005-04-27 | — | — | CN | disclosed |