Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583079 | 0.78 | CHRM2 (0.50) | ENPP2PTGS2PTGS1 | |
| SCHEMBL9451016 | 0.78 | MEN1 (0.44) | HTT | |
| SCHEMBL27596080 | 0.77 | PKM (0.53) | HTT | |
| SCHEMBL27810182 | 0.73 | ALDH1A1 (0.49) | ENPP2PTGS2PTGS1AKR1C3RIPK1 | |
| SCHEMBL6283941 | 0.73 | KMT2A (0.44) | ENPP2PTGS2 | |
| SCHEMBL13176976 | 0.72 | PTGS2 (0.51) | ENPP2PTGS2PTGS1HTTGPR119 | |
| SCHEMBL2376239 | 0.72 | ENPP2 (0.72) | ENPP2PTGS2 | |
| SCHEMBL30172475 | 0.72 | ENPP2 (0.43) | ENPP2PTGS2PTGS1AKR1C3RIPK1 | |
| SCHEMBL15771678 | 0.72 | CA2 (0.43) | PTGS2HTT | |
| SCHEMBL5342271 | 0.72 | CCNB2 (0.38) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166585-B2 | 24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D3 | CYTOCHROMA INC. (CA) | 2007-01-23 | — | — | US | disclosed |