Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | IDO1 | P14902 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.50 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17283552 | 0.86 | ALOX15 (0.81) | ALOX15IDO1NPC1RAB9AHPGD | |
| SCHEMBL23162526 | 0.82 | IDO1 (0.56) | ALOX15IDO1NPC1RAB9AHPGD | |
| SCHEMBL29446652 | 0.82 | IDO1 (0.56) | ALOX15IDO1NPC1RAB9AHPGD | |
| SCHEMBL8290846 | 0.81 | ALOX15 (1.00) | ALOX15IDO1NPC1RAB9AHPGD | |
| SCHEMBL6323134 | 0.77 | IDO1 (0.42) | ALOX15IDO1NPC1RAB9AHPGD | |
| SCHEMBL27614805 | 0.77 | ALOX15 (0.65) | ALOX15IDO1NPC1RAB9ATSHR | |
| SCHEMBL21281903 | 0.77 | L3MBTL1 (0.53) | IDO1NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL27614878 | 0.77 | ALOX15 (0.65) | ALOX15IDO1HPGDMAPTMAPK9 | |
| SCHEMBL8214957 | 0.75 | ALOX15 (0.70) | ALOX15IDO1NPC1RAB9AHPGD | |
| SCHEMBL12469894 | 0.74 | NPC1 (0.50) | IDO1NPC1RAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438376-B | 4, 5-diheteroaryl substituted triazole compound and preparation method and application thereof | 扬州工业职业技术学院 | 2020-09-04 | — | — | CN | disclosed |
| CN-109438375-B | Preparation method of 4, 5-diphenyl substituted triazole compound | 扬州工业职业技术学院 | 2020-09-01 | — | — | CN | disclosed |
| CN-109433180-A | A kind of biological carbon load alkali and its application as catalyst | 扬州工业职业技术学院 | 2019-03-08 | — | — | CN | disclosed |
| CN-109438375-A | A kind of preparation method for the triazole class compounds that 4,5- diphenyl replaces | 扬州工业职业技术学院 | 2019-03-08 | — | — | CN | disclosed |
| CN-109438376-A | A kind of bis- heteroaryl substituted triazole compounds of 4,5- and the preparation method and application thereof | 扬州工业职业技术学院 | 2019-03-08 | — | — | CN | disclosed |
| CN-1608065-A | Phenyl substituted triazoles and their use as selective inhibors of akl5 kinase and pharmaceutical compositions containing the compounds | SMITHKLINE BEECHAM CORP (US) | 2005-04-20 | — | — | CN | disclosed |