Sugi Predict

Sugi Predict / Compounds / SCHEMBL17283552

SCHEMBL17283552

SCHEMBL17283552

c1ccc(-c2n[nH]nc2-c2cccc(-c3n[nH]nc3-c3ccccc3)c2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.81
▸ LMNA P02545 3/20 0.53
▸ KDM4E B2RXH2 3/20 0.53
▸ ERBB2 P04626 1/20 0.53
▸ HPGD P15428 4/20 0.52
▸ GAA P10253 3/20 0.52
▸ MAPT P10636 2/20 0.52
▸ MAPK10 P53779 3/20 0.52
▸ MAPK9 P45984 2/20 0.52
▸ MAPK8 P45983 1/20 0.52
▸ HSP90AA1 P07900 1/20 0.49
▸ GP6 Q9HCN6 1/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ ALDH1A1 P00352 4/20 0.45
▸ GFER P55789 1/20 0.45
▸ ALPL P05186 1/20 0.43
▸ IDO1 P14902 1/20 0.43
▸ TTK P33981 1/20 0.43
▸ ATM Q13315 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8290846 0.90 ALOX15 (1.00) ALOX15LMNAKDM4EERBB2HPGD
SCHEMBL27614805 0.86 ALOX15 (0.65) ALOX15LMNAKDM4EERBB2SMN1; SMN2
SCHEMBL27614878 0.86 ALOX15 (0.65) ALOX15LMNAKDM4EERBB2HPGD
SCHEMBL27596103 0.86 ALOX15 (0.65) ALOX15LMNAKDM4EERBB2HPGD
SCHEMBL17283683 0.83 ALOX15 (0.68) ALOX15LMNAKDM4EERBB2HPGD
SCHEMBL28042278 0.77 ALOX15 (0.74) ALOX15LMNAKDM4EERBB2HPGD
SCHEMBL18385895 0.74 ADORA1 (0.56) ALOX15LMNAKDM4EHPGDMAPT
SCHEMBL8214957 0.74 ALOX15 (0.70) ALOX15LMNAKDM4EERBB2HPGD
SCHEMBL27216964 0.74 ALOX15 (0.70) ALOX15LMNAKDM4EERBB2HPGD
SCHEMBL10166458 0.74 ALOX15 (0.70) ALOX15LMNAKDM4EERBB2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149206-A1 METHOD FOR PRODUCING ACRYLIC RESIN FILM コニカミノルタ株式会社 2020-07-23 — — WO disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed
US-20150099780-A1 DEUTERATED CFTR POTENTIATORS VERTEX PHARMACEUTICALS (EUROPE) LIMITED (GB) 2015-04-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS ALOX15 1176/4885LMNA 2915/4885KDM4E 2732/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 ALOX15 1404/4885LMNA 2773/4885KDM4E 1554/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 ALOX15 3195/4885LMNA 3412/4885KDM4E 3237/4885
US-20150099780-A1 DEUTERATED CFTR POTENTIATORS CFTR, SLC26A3, SLC26A4 ALOX15 2201/4885LMNA 4048/4885KDM4E 4762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.