Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 13/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580101 | 0.79 | KMT2A (0.45) | KMT2AFBP1ALDH1A1MAPTHPGD | |
| SCHEMBL10767304 | 0.77 | KMT2A (0.43) | KMT2AFBP1ALDH1A1MAPTNLRP3 | |
| SCHEMBL6098151 | 0.77 | KMT2A (0.52) | KMT2AFBP1ALDH1A1MAPTHPGD | |
| SCHEMBL10764574 | 0.75 | KMT2A (0.44) | KMT2AFBP1ALDH1A1MAPTHPGD | |
| M-Xylene SCHEMBL27256278 | 0.74 | ACHE (0.57) | ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL10765775 | 0.74 | KMT2A (0.49) | KMT2AFBP1ALDH1A1MAPTHPGD | |
| SCHEMBL28327825 | 0.72 | NLRP3 (0.45) | KMT2AFBP1ALDH1A1MAPTHPGD | |
| SCHEMBL6095780 | 0.72 | KMT2A (0.44) | KMT2AFBP1ALDH1A1NLRP3 | |
| SCHEMBL9733973 | 0.72 | KMT2A (0.50) | KMT2AFBP1ALDH1A1MAPTNLRP3 | |
| SCHEMBL13656915 | 0.72 | KMT2A (0.50) | KMT2AFBP1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1642929-B | Kappa-opioid receptor agonists containing 2-phenylbenzothiazoline derivatives | SANTEN PHARMACEUTICAL CO LTD | 2010-05-12 | — | — | CN | disclosed |
| CN-100522954-C | Kappa-opioid receptor agonist composed of 2-phenylbenzothiazoline derivative | SANTEN PHARMACEUTICAL CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |
| CN-1911918-A | Kappa-opioid receptor agonist composed of 2-phenylbenzothiazoline derivative | SANTEN PHARMACEUTICAL CO LTD (JP) | 2007-02-14 | — | — | CN | disclosed |
| CN-1642929-A | Kappa-opioid receptor agonists containing 2-phenylbenzothiazoline derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 2005-07-20 | — | — | CN | disclosed |