Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27596182 | 0.90 | MAPK13 (0.43) | CTNNB1WNT3AALDH1A1LMNAGLA | |
| SCHEMBL27596328 | 0.88 | MAPK13 (0.51) | ALDH1A1MAPT | |
| SCHEMBL27596193 | 0.88 | PKM (0.44) | CTNNB1WNT3AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27596183 | 0.87 | ALDH1A1 (0.40) | HTTALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL27615061 | 0.82 | LIMK1 (0.41) | — | |
| SCHEMBL27596189 | 0.81 | MAPK13 (0.37) | — | |
| SCHEMBL5564938 | 0.81 | MAPK13 (0.44) | — | |
| SCHEMBL27614965 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL27596159 | 0.78 | MAPK13 (0.44) | — | |
| SCHEMBL5564934 | 0.77 | MAPK13 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100363362-C | Thiazole derivatives as NPY receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-01-23 | — | — | CN | disclosed |
| CN-1639158-A | Thiazole derivatives as NPY receptor antagonists | HOFFMANN LA ROCHE (CH) | 2005-07-13 | — | — | CN | disclosed |