Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565893 | 0.86 | AMY1A (0.47) | TYRALOX15TP53TDP1MAPT | |
| SCHEMBL8400481 | 0.85 | TYR (0.58) | TYRALOX15TP53TDP1MAPT | |
| SCHEMBL28858657 | 0.83 | TYR (0.53) | TYRALOX15TP53TDP1MAPT | |
| SCHEMBL27818642 | 0.83 | ALOX15 (0.50) | TYRALOX15TP53TDP1MAPT | |
| SCHEMBL25995101 | 0.81 | BCHE (0.49) | TYRALOX15TP53TDP1MAPT | |
| SCHEMBL25995100 | 0.81 | BCHE (0.49) | TYRALOX15TP53TDP1MAPT | |
| Amylmetacresol SCHEMBL29897625 | 0.80 | TYR (0.68) | TYRALOX15TP53TDP1MAPT | |
| Amylmetacresol SCHEMBL302197 | 0.80 | TYR (0.68) | TYRALOX15TP53TDP1MAPT | |
| SCHEMBL25995102 | 0.80 | MEN1 (0.43) | TYRALOX15TP53TDP1MAPT | |
| SCHEMBL25995097 | 0.80 | MEN1 (0.43) | TYRALOX15TP53TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100516031-C | Organic multiple isocyanate composition | MITSUI TAKEDA CHEMICAL CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-1626509-A | Organic multiple isocyanate compsn. | MITSUI TAKEDA CHEMICAL CO LTD (JP) | 2005-06-15 | — | — | CN | disclosed |