Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glucametacin SCHEMBL30344903 | 0.86 | PTGS2 (0.72) | PTGS2 | |
| Glucametacin SCHEMBL27641193 | 0.86 | PTGS2 (0.72) | PTGS2 | |
| Glucametacin SCHEMBL5081097 | 0.86 | PTGS2 (0.72) | PTGS2 | |
| Glucametacin SCHEMBL24511 | 0.86 | PTGS2 (0.72) | PTGS2 | |
| SCHEMBL11263049 | 0.79 | PTGS2 (0.74) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL27617617 | 0.79 | PTGS2 (0.65) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL14086813 | 0.78 | PTGS2 (1.00) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| SCHEMBL30426824 | 0.78 | PTGS2 (1.00) | PTGS2AKR1C3CNR2PTGS1KDM4E | |
| Glucametacin SCHEMBL9988209 | 0.78 | PTGS2 (0.63) | PTGS2 | |
| Indomethacin SCHEMBL8509782 | 0.77 | PTGS2 (0.74) | PTGS2AKR1C3CNR2PTGS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1616474-A | Acetamido glucose devicative of indomethacin and its synthetic method and use | CHINA OCEANOGRAPHIC UNIV (CN) | 2005-05-18 | — | — | CN | disclosed |