Glucametacin

Glucametacin

SCHEMBL27641193

COc1ccc2c(c1)c(CC(=O)NC(C=O)C(O)C(O)C(O)CO)c(C)n2C(=O)c1ccc(Cl)cc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glucametacin SCHEMBL24511 1.00 PTGS2 (0.72) PTGS2
Glucametacin SCHEMBL30344903 1.00 PTGS2 (0.72) PTGS2
Glucametacin SCHEMBL5081097 1.00 PTGS2 (0.72) PTGS2
Glucametacin SCHEMBL9988209 0.91 PTGS2 (0.63) PTGS2
Indomethacin SCHEMBL8509782 0.86 PTGS2 (0.74) PTGS2
SCHEMBL5080287 0.86 PLA2G2A (0.65) PTGS2
SCHEMBL5080284 0.86 PLA2G2A (0.65) PTGS2
SCHEMBL27599208 0.86 PTGS2 (0.62) PTGS2
SCHEMBL11263049 0.85 PTGS2 (0.74) PTGS2
SCHEMBL11263058 0.84 PTGS2 (0.67) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1747731-A Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders ALTANA PHARMA AG (DE) 2006-03-15 CN claimed
CN-110658337-B Diagnosis and treatment of autoimmune diseases 武田药品工业株式会社 2023-06-16 CN disclosed