Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16516540 | 0.80 | L3MBTL1 (0.44) | L3MBTL1NQO2KDM4EMAPTALDH1A1 | |
| SCHEMBL16008667 | 0.80 | L3MBTL1 (0.44) | L3MBTL1ADORA3NQO2KDM4EUSP2 | |
| SCHEMBL2990475 | 0.80 | ADORA3 (0.42) | L3MBTL1ADORA3KDM4EUSP2HTT | |
| SCHEMBL2212160 | 0.79 | ACACB (0.41) | L3MBTL1ADORA3NQO2KDM4EHTT | |
| SCHEMBL2215224 | 0.77 | ALDH1A1 (0.51) | L3MBTL1KDM4EAHRHTTMAPT | |
| SCHEMBL28328752 | 0.77 | L3MBTL1 (0.44) | L3MBTL1NQO2KDM4EUSP2HTT | |
| SCHEMBL28327541 | 0.77 | HTR2A (0.48) | L3MBTL1NQO2KDM4EMAPTALDH1A1 | |
| SCHEMBL14693670 | 0.77 | L3MBTL1 (0.44) | L3MBTL1ADORA3NQO2KDM4EHTT | |
| SCHEMBL27529060 | 0.75 | RAD52 (0.44) | L3MBTL1KDM4EHTTMAPTALDH1A1 | |
| SCHEMBL10527114 | 0.72 | L3MBTL1 (0.40) | L3MBTL1NQO2KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100351251-C | Indolylmaleimide derivatives | NOVARTIS AG (CH) | 2007-11-28 | — | — | CN | disclosed |
| CN-1639153-A | Indolylmaleimide derivatives | NOVARTIS AG (CH) | 2005-07-13 | — | — | CN | disclosed |