SCHEMBL27600474

SCHEMBL27600474

CC1CCC(C)(C(c2ccccc2)c2ccccc2)CC1.N=C=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
SIGMAR1 Q99720 2/20 0.34
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NR1I2 O75469 1/20 0.32
ABCB11 O95342 1/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
PTPN1 P18031 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27600473 1.00 CYP2C9 (0.36) CYP2C9CYP2C19SIGMAR1ALDH1A1KDM4E
SCHEMBL30111553 0.67
SCHEMBL4749593 0.67 USP2 (0.47) CYP2C9CYP2C19SIGMAR1ALDH1A1MEN1
Diphenylmethane SCHEMBL6473335 0.66 CALM1 (0.46) CYP2C19SIGMAR1ALDH1A1LMNAKMT2A
SCHEMBL18536036 0.66 LMNA (0.46) CYP2C9CYP2C19LMNAHPGDSMN1; SMN2
Naphthalene SCHEMBL28099215 0.64 NPC1 (0.38) CYP2C9CYP2C19ALDH1A1KDM4ELMNA
SCHEMBL4808563 0.63 DAO (0.41) ALDH1A1KDM4ELMNAKMT2A
SCHEMBL132503 0.63 DAO (0.41) ALDH1A1KDM4ELMNAKMT2A
Isopropylbenzene SCHEMBL133881 0.63 CYP2C9 (0.41) CYP2C9ALDH1A1KDM4ELMNAHPGD
Isopropylbenzene SCHEMBL1347599 0.63 CYP2C9 (0.41) CYP2C9ALDH1A1KDM4ELMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1656188-A In-mold appearance coatings for nylon and nylon based thermoplastic substrates OMNOVA SOLUTIONS INC (US) 2005-08-17 CN disclosed