Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.32 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600865 | 1.00 | TMEM97 (0.40) | TMEM97SIGMAR1ALDH1A1NPSR1NAMPT | |
| SCHEMBL5629206 | 0.76 | AADAT (0.45) | TMEM97SIGMAR1ALDH1A1NPSR1NAMPT | |
| SCHEMBL5629328 | 0.76 | AADAT (0.45) | TMEM97SIGMAR1ALDH1A1NPSR1NAMPT | |
| SCHEMBL27479625 | 0.71 | MTNR1A (0.40) | MEN1LMNAKMT2AAADATGOT1 | |
| SCHEMBL27600884 | 0.71 | CACNA1S (0.42) | SIGMAR1ALDH1A1NPSR1HTR1AADRA1A | |
| SCHEMBL28752169 | 0.71 | AADAT (0.40) | ALDH1A1KMT2AAADATGOT1KYAT1 | |
| SCHEMBL27619296 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AAADAT | |
| SCHEMBL13232574 | 0.68 | ALDH1A1 (0.47) | TMEM97SIGMAR1ALDH1A1NPSR1NAMPT | |
| SCHEMBL5629787 | 0.65 | AADAT (0.48) | LMNAAADATGOT1NOTUMKYAT1 | |
| SCHEMBL7434719 | 0.63 | ALDH1A1 (0.52) | TMEM97SIGMAR1ALDH1A1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100384852-C | Heterocyclic amide derivatives as inhibitors of glycogen phoshorylase | ASTRAZENECA AB (SE) | 2008-04-30 | — | — | CN | disclosed |
| CN-1653070-A | Heterocyclic amide derivatives as inhibitors of glycogen phoshorylase | ASTRAZENECA AB (SE) | 2005-08-10 | — | — | CN | disclosed |