Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618508 | 0.88 | ALDH1A1 (0.46) | FFAR4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL489064 | 0.87 | ALDH1A1 (0.45) | FFAR4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL4451323 | 0.86 | TSHR (0.47) | FFAR4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL7219535 | 0.86 | NPC1 (0.44) | FFAR4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL3921415 | 0.86 | CYP4A11 (0.54) | FFAR4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL27523349 | 0.85 | GAA (0.50) | FFAR4ALDH1A1GAAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL12499751 | 0.84 | LMNA (0.47) | FFAR4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL8252765 | 0.83 | GAA (0.47) | FFAR4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL23582779 | 0.83 | FFAR4 (0.61) | FFAR4ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18030873 | 0.83 | PLA2G2A (0.53) | FFAR4ALDH1A1GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101896470-B | Dual-acting benzimidazole derivatives and their use as antihypertensive agents | THERAVANCE INC | 2013-04-10 | — | — | CN | disclosed |
| CN-101896470-A | Dual-acting benzimidazole derivatives and their use as antihypertensive agents | THERAVANCE INC | 2010-11-24 | — | — | CN | disclosed |
| CN-1922151-A | Substituted azole derivatives, compositions, and methods of use | TRANSTECH PHARMA INC (US) | 2007-02-28 | — | — | CN | disclosed |
| CN-1606553-A | Oxytocin agonistenoxytocin agonisten | FERRING BV (NL) | 2005-04-13 | — | — | CN | disclosed |