Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956653 | 0.72 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL5344409 | 0.72 | KMT2A (0.48) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL10351264 | 0.70 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL149632 | 0.69 | — | — | |
| SCHEMBL25137339 | 0.68 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL2320794 | 0.68 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL28196597 | 0.68 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAGAACES2 | |
| SCHEMBL812709 | 0.68 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL1668498 | 0.68 | F2 (0.46) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7087951 | 0.68 | KMT2A (0.45) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1656095-A | Spiro derivatives and adhesion molecule inhibitors comprising the same as the active ingredient | TORAY INDUSTRIES (JP) | 2005-08-17 | — | — | CN | disclosed |