Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747734 | 0.87 | KMT2A (0.57) | KDM4ECYP1A2HSD17B10KMT2AALDH1A1 | |
| SCHEMBL27508538 | 0.86 | LMNA (0.41) | KDM4ECYP1A2HSD17B10KMT2AALDH1A1 | |
| SCHEMBL3437042 | 0.81 | KDM4E (0.48) | KDM4ECYP1A2HSD17B10KMT2AALDH1A1 | |
| SCHEMBL27392797 | 0.76 | TSHR (0.48) | HSD17B10KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27468102 | 0.74 | KMT2A (0.74) | HSD17B10KMT2AALDH1A1USP2L3MBTL1 | |
| SCHEMBL8747754 | 0.71 | KMT2A (0.43) | KDM4ECYP1A2HSD17B10KMT2AALDH1A1 | |
| SCHEMBL8754736 | 0.71 | KDM4E (0.40) | KDM4ECYP1A2HSD17B10KMT2AALDH1A1 | |
| SCHEMBL27924444 | 0.71 | ALDH1A1 (0.39) | KMT2AALDH1A1LMNATSHR | |
| SCHEMBL16896666 | 0.69 | BCAT2 (0.51) | CYP1A2KMT2ALMNATSHRGAA | |
| SCHEMBL2634661 | 0.69 | KDM4E (0.48) | KDM4ECYP1A2HSD17B10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649830-A | Substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-08-03 | — | — | CN | claimed |
| CN-1649830-A | Substituted aryl ketones | BAYER CROPSCIENCE AG (DE) | 2005-08-03 | — | — | CN | disclosed |